The present study was carried out to evaluate and compare anti-inflammatory activity of Brihatpanchamoola Kwatha prepared by root bark and stem bark of Brihatpanchamoola in Carrageenan induced paw oedema model. Wister strain albino rats of either sex were selected and divided in to four groups of 6 animals each. The test drug was administered orally at a dose of 9 ml/kg body weight of rat. Phenylbutazone was used as standard anti-inflammatory drug for comparison. Both the samples of Brihatpanchamoola Kwatha have shown inhibition of carrageenan induced paw oedema, however significant inhibition was observed only in stem bark sample treated group. This study shows that Brihatpanchamoola Kwatha prepared from stem bark samples have significant anti-inflammatory activity. Hence it can be preferred in the non-availability of root samples.
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